FISHER SCIENTIFIC -- PHENOLPHTHALEIN SOLUTION 1%, S71429 -- 6810-00N091322
===================== Product Identification ===================== Product ID:PHENOLPHTHALEIN SOLUTION 1%, S71429 MSDS Date:10/01/1998 FSC:6810 NIIN:00N091322 Status Code:A === Responsible Party === Company Name:FISHER SCIENTIFIC Address:1 REAGENT LANE City:FAIRLAWN State:NJ ZIP:07410 Country:US Info Phone Num:201-796-7100 Emergency Phone Num:201-796-7100 Resp. Party Other MSDS Num.:ACC#45376 Chemtrec Ind/Phone:(800)424-9300 CAGE:1B464 === Contractor Identification === Company Name:FISHER SCIENTIFIC CO. CHEMICAL MFG DIV Address:1 REAGENT LANE Box:City:FAIRLAWN State:NJ ZIP:07410-2802 Country:US Phone:201-796-7100 CAGE:1B464 ============= Composition/Information on Ingredients ============= Ingred Name:ISOPROPYL ALCOHOL. LD50:(ORAL,RAT) 5045 MG/KG. EXPOSURE LIMITS: NIOSH - 400 PPM TWA; 980 MG/M3 TWA; 2000 PPM IDLH (10% LOWER EXPLO LIMIT). EINECS/ELINC = 200-661-7. CAS:67-63-0 RTECS #:NT8050000 = Wt:99. OSHA PEL:980 MG/M3;400 PPM ACGIH TLV:983 MG/M3;400 PPM ACGIH STEL:1230 MG/M3;500 PPM Ingred Name:PHENOLPHTHALEIN. EINECS/ELINC = 201-004-7. CAS:77-09-8 RTECS #:SM8380000 = Wt:1. ===================== Hazards Identification ===================== LD50 LC50 Mixture:SEE INGREDIENTS & TOXICOLOGICAL INFO. Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO Health Hazards Acute and Chronic:ACUTE:EYE:MAY CAUSE IRRIT. PRDCES IRRIT, CHARACT BY BURNING SENSATION, REDNESS, TEARING INFLAMM & POSS CORNEAL INJURY. SKIN:MAY CAUSE IRRIT. MAY CAUSE SENSIT, ALLERGIC RXN, WHICH BECOMES EVID UPON RE- EXPOS TO THIS MATL. PRLNG &/OR RPTD CONT MAY CAUSE DEFAT OF SKIN & DERM. MAY CAUSE IRRIT W/PAIN & STINGING, ESP IF SKIN IS ABRADED. MAY BE ABSORBED THRU SKIN. INGEST:MAY CAUSE IRRIT OF DIGEST TRACT. M AY CAUSE GI IRRIT W/NAUS, VOMIT & DIARR. MAY CAUSE KIDNEY DMG. MAY CAUSE CNS DEPRESS, CHARACT BY EXCITEMENT, FOLLOWED BY HDCH, DIZZ, DROW, COMA & POSS DEATH DUE TO RESP FAILURE. EXPECTED TO BE LOW ING EST HAZ. INHAL:INHAL OF(EFTS OF OVEREXP) Explanation of Carcinogenicity:ISOPROPYL ALCOHOL - CAS #67-63-0; IARC: GROUP 3 CARCINOGEN. PHENOLPHTHALEIN - CAS #77-09-8; NOT LISTED BY ACGIH, IARC, NIOSH, NTP OR OSHA. Effects of Overexposure:HLTH HAZ:HIGH CONCS MAY CAUSE CNS EFTS CHARACT BY HDCH, DIZZ, UNCON & COMA. MAY CAUSE RESP TRACT IRRIT. INHAL OF VAP MAY CAUSE RESP TRACT IRRIT. LOW HAZ FOR USUAL INDUS HNDLG. CHRONIC: POSS CANCER HAZ BASED ON TESTS W/LAB ANIMALS. PRLNG/RPTD SKIN CONT MAY CAUSE DEFAT & DERM. MAY CAUSE KIDNEY INJURY. MAY CAUSE CANCER ACCORDING TO ANIMAL STUDIES. MAY CAUSE ALLERGIC SKIN RXN IN SOME INDIVIDUALS. MAY CAUSE REPRO & FETAL EFTS. TARGET ORGANS: KIDNEYS, CENTRAL NERVOUS SYSTEM. ======================= First Aid Measures ======================= First Aid:EYES:IMMED FLUSH W/PLENTY OF WATER FOR AT LST 15 MINS, OCCAS LIFTING UPPER & LOWER LIDS. GET MED AID IMMED. SKIN:FLUSH W/PLENTY OF SOAP & WATER FOR AT LST 15 MINS WHILE REMOVING CONTAM CLTHG & SHOES. GET MED AID IF IRRIT DEVELS/PERSISTS. FLUSH SKIN W/PLENTY OF SOAP & WATER. INGEST:IF VICTIM IS CONSCIOUS & ALERT, GIVE 2-4 CUPFULS OF MILK/WATER. NEVER GIVE ANYTHING BY MOUTH TO UNCON PERS. GET MED AI D IMMED IF IRRIT/SYMPS OCCUR. INHAL:REMOVE FROM EXPOS TO FRESH AIR IMMED. IF NOT BRTHG, GIVE ARTF RESP. IF BRTHG IS DFCLT, GIVE OXYG. GET MED AID IMMED IF COUGH/OTHER SYMPS APPEAR. NOTE TO MD:TREAT SY MPTOMATICALLY & SUPPORTIVELY. ===================== Fire Fighting Measures ===================== Flash Point:=12.8C, 55.F Autoignition Temp:=398.9C, 750.F Lower Limits:2.0% Upper Limits:12.7% Extinguishing Media:FOR SMALL FIRES, USE DRY CHEMICAL, CARBON DIOXIDE, WATER SPRAY OR ALCOHOL-RESISTANT FOAM. FOR SMALL FIRES, USE WATER SPRAY, DRY CHEMICAL, CARBON DIOXIDE OR CHEMICAL FOAM. Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE EQUIPMENT . VAPORS CAN TRAVEL TO A SOURCE OF IGNITION & FLASH BACK. USE WATER SPRAY TO COOL FIRE-EXPOSED CONTAINERS. WATER MAY BE INEFFECTIVE. Unusual Fire/Explosion Hazard:CNTNRS MAY EXPLODE IN HEAT OF FIRE. THIS CHEM POSES AN EXPLOSION HAZ. MAY FORM EXPLOSIVE PEROXIDES. VAPS MAY BE HVR/AIR. THEY CAN SPREAD ALONG THE GROUND & COLLECT IN LOW OR CONFINED AREAS. NFPA RATIN G: NOT PUBLISHED. ================== Accidental Release Measures ================== Spill Release Procedures:USE PROPER PPE AS INDICATED IN EXPOS CONTROLS, PERSONAL PROT SECTION. ABSORB SPILL W/INERT MATL (E.G., DRY SAND/EARTH), THEN PLACE INTO CHEM WASTE CNTNR. SWEEP UP, THEN PLACE INTO SUITABLE CNTNR FOR D ISP. REMOVE ALL SOURCES OF IGNIT. ====================== Handling and Storage ====================== Handling and Storage Precautions:USE SPK-PROOF TOOLS & EXPLO PROOF EQUIP. AVOID CONT W/EYES, SKIN & CLTHG. EMPTY CNTNRS RETAIN PROD RESIDUE, (LIQ &/OR VAP) & CAN BE DANGEROUS. KEEP CNTNR TIGHTLY CLSD. AVOID INGEST & INHAL. DO NOT PRE SSURIZE, CUT, WELD, BRAZE, SOLDER, DRILL, GRIND/EXPOSE EMPTY CNTNRS TO HEAT, SPKS/OPEN FLAMES. Other Precautions:USE W/ADEQ VENT. KEEP AWAY FROM HEAT, SPKS & FLAME. KEEP AWAY FROM SOURCES OF IGNIT. KEEP CNTNR CLSD WHEN NOT IN USE. KEEP FROM CONT W/OXIDIZING MATLS. STORE IN COOL, DRY, WELL-VENTED AREA AWAY FROM I NCOMPAT SUBSTANCES. ============= Exposure Controls/Personal Protection ============= Respiratory Protection:A NIOSH APPRVD/EUROPEAN STD EN 149 AIR PURIFYING RESP W/ORG VAP CARTRIDGE/CANISTER MAY BE PERMISSIBLE UNDER CERTAIN CIRCUMSTANCES WHERE AIRBORNE CONCS ARE EXPECTED. A RESP PROT PROGRAM THAT MEETS OSHA 'S 29 CFR 1910.134 & ANSI Z88.2 REQUIREMENTS/EUROPEAN STD EN 149 MUST BE FOLLOWED WHENEVER WORKPLACE CNDTNS WARRANT RESP'S USE. FOLLOW OSHA RESP (SUPP DATA) Ventilation:GOOD GENERAL VENT SHOULD BE SUFFICIENT TO CONTROL AIRBORNE LEVELS. USE ADEQUATE GENERAL OR LOCAL EXHAUST VENT TO KEEP AIRBORNE CONCS BELOW PELS. Protective Gloves:IMPERVIOUS GLOVES . Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES . Other Protective Equipment:EYE WASH & DELUGE SHOWER MEETING ANSI DESIGN CRITERIA . WEAR APPROP PROT CLTHG TO MIN CONT W/SKIN OR TO PREVENT SKIN EXPOS. Work Hygienic Practices:WASH THORO AFTER HNDLG. WASH HANDS BEFORE EATING. REMOVE CONTAM CLTHG & WASH BEFORE REUSE. Supplemental Safety and Health RESP PROT:REGS FOUND IN 29 CFR 1910.134/EUROPEAN STD EN 149. ALWAYS USE NIOSH/EUROPEAN STD EN 149 NIOSH APPRVD RESP WHEN NEC. PHYSICAL DATA: MOLECULAR FORMULA:MIXTURE. TOX INFO:NEUROTOXICITY:NO DATA A VAIL. MUTAGENICITY:SIGNIFICANT INCRS IN CHROMOSOMAL ABERRATIONS WERE OBSERVED AFTER TREATMENT OF CULTURED (OTHER INFO) ================== Physical/Chemical Properties ================== Boiling Pt:=83.C, 181.4F Melt/Freeze Pt:=89.C, 192.2F Decomp Temp:Decomp Text:NOT AVAILABLE Vapor Pres:40 MM HG Vapor Density:2.1 Spec Gravity:0.7855 pH:NOT AVAILABLE Viscosity:NOT AVAILABLE Solubility in Water:SOLUBLE Appearance and Odor:COLORLESS LIQUID; ALCOHOL-LIKE ODOR. ================= Stability and Reactivity Data ================= Stability Indicator/Materials to Avoid:YES OXIDIZING AGENTS, ISOPROPANOL IS SUSCEPTIBLE TO AUTOXIDATION & THEREFORE SHOULD BE CLASSIFIED AS PEROXIDIZABLE. Stability Condition to Avoid:THIS MATERIAL MAY BE SENSITIVE TO PEROXIDE FORMATION, INCOMPATIBLE MATERIALS, IGNITION SOURCES, EXCESS HEAT. Hazardous Decomposition Products:CARBON MONOXIDE, CARBON DIOXIDE, ACRID SMOKE & FUMES. Conditions to Avoid Polymerization:WILL NOT OCCUR. =================== Toxicological Information =================== Toxicological Information:LD50/LC50:CAS #67-63-0: LD50:(ORAL,MOUSE) 3600 MG/KG; LD50:(ORAL,RABBIT) 6410 MG/KG; LD50:(SKIN,RABBIT) 12,800 MG/KG. EPIDEMIOLOGY:NTP REPORTED THAT THERE WAS CLEAR EVID OF CARCIN ACTIVITY IN MALE RAT S BASED ON MARKEDLY INCRD INCIDENCES OFBENIGN PHEOCHROMOCYTOMA OF ADRENAL MEDULLA & OTHERS. THERE WAS CLEAR EVID IN MICE BASED ON INCR INCIDENCES OF HISTIOCYTIC SARCOMA & MALIGNANT LYMPHOMA OF THYMIC ORIGIN. THERE WAS ALSO CLEAR EVID IN FEMALE MICE BASED ON INCR INCIDENCES OF HISTIOCYTIC SARCOMA, MALIGNANT LYMPHOMAS & BENIGN SEX-CORD STROMAL TUMORS OF OVARY. TERATOGENICITY:NO DATA AVAIL. REPRO EFT S:NO DATA AVAIL.(SUPP DATA) ===================== Ecological Information ===================== Ecological:ECOTOXICITY:NOT AVAIL. ENVIRON FATE:NOT AVAIL. PHYSICAL/CHEM:NOT AVAIL. OTHER:NOT AVAIL. -- OTHER INFO:PHRASES:S16 KEEP AWAY FROM SOURCES OF IGNIT - NO SMOKING. S24/25 AVOID CONT W/SKIN & EYES. WGK (W ATER DANGER/PROT):CAS #67-63-0: 1; CAS #77-09-8: 1. CANADA: CAS #67-63-0 IS LISTED ON CANADA'S DSL/NDSL LIST. CAS #77-09-8 IS LISTED ON CANADA'S DSL/NDSL LIST. THIS PROD HAS WHMIS CLASSIFICATION OF B2 , D2B. CAS #67-63-0 IS NOT LISTED ON CANADA'S ING DISCLOSURE LIST. CAS # 77-09-8 IS NOT LISTED ON CANADA'S ING DISCLOSURE LIST. EXPOS LIMS: CAS #67-63-0: OEL-AUSTRALIA:TWA 400 PPM (980 MG/M3); STEL 50 0 PPM (1225 MG/M3) (TRANSPORT INFO) ==================== Disposal Considerations ==================== Waste Disposal Methods:DISPOSE OF IN A MANNER CONSISTENT W/FEDERAL, STATE & LOCAL REGULATIONS. RCRA D-SERIES MAXIMUM CONCENTRATION OF CONTAMINANTS: NONE LISTED. RCRA D-SERIES CHRONIC TOXICITY REFERENCE LEVELS: NONE LISTED. RCRA F-SERIES: NONE LISTED. RCRA P-SERIES: NONE LISTED. RCRA U-SERIES: NONE LISTED. =================== MSDS Transport Information =================== Transport Information:U.S. DOT:SHIPPING NAME:FLAMM LIQ, N.O.S. (CNTNS 2-PROPANOL). HAZ CLASS: 3. UN #:UN1993. PACKING GRP:II. IATA:SHIPPING NAME:NO INFO AVAIL. RID/ADR:SHIPPING NAME:NO INFO AVAIL. IMO: SHIPPING NAME:NO INF O AVAIL. FLAMM LIQ N.O.S. (2-PROPANOL). HAZ CLASS: 3. UN #:UN1993. PACKING GRP:II. ADDNL INFO:FL PT 12C. -- ECOLOGICAL INFO:OEL-BELGIUM:TWA 400 PPM (985 MG/M3); STEL 500 PPM (1230 MG/M3) OEL-DENMARK:T WA 200 PPM (490 MG/M3); SKIN OEL-FRANCE:STEL 400 PPM (980 MG/M3) OEL GERMANY:TWA 400 PPM (980 MG/M3) OEL-JAPAN:STEL 400 PPM (980 MG/M3) OEL-THE NETHERLANDS:TWA 400 PPM (980 MG/M3); SKIN OEL-THE PHILIP PINES:TWA 400 PPM (SARA TITLE III) ===================== Regulatory Information ===================== SARA Title III Information:SECTION 302 (RQ & TPQ):NONE OF CHEMS IN THIS MATL HAVE RQ/TPQ. SARA CODES:CAS #67-63-0:ACUTE, CHRONIC, FLAMM. CAS #77-09-8:ACUTE. SECTION 313: THIS MATL CNTNS ISOPROPYL ALCOHOL (CAS #67-63-0, 99%), WH ICH IS SUBJECT TO REPORTING REQUIREMENTS OF SECTION 313 OF SARA TITLE III & 40 CFR PART 373. -- TRANSPORT INFO:(980 MG/M3) OEL-RUSSIA:STEL 400 PPM (10 MG/M3 OEL-SWEDEN:TWA 150 PPM (350 MG/M3; STEL 250 PPM (600 MG/M3) OEL-SWITZERLAND:TWA 400 PPM (980 MG/M3); STEL 800 PPM OEL-TURKEY:TWA 200 PPM (500 MG/M3 OEL-UNITED KINGDOM:TWA 400 PPM (980 MG/M3); STEL 500 PPM; SKIN OEL IN BULGARIA, COLOMBIA, JORDA N, KOREA CHECK (STATE REGULATORY INFO) Federal Regulatory Information:TSCA:CAS #67-63-0 IS LISTED ON TSCA INVENTORY. CAS #77-09-8 IS LISTED ON TSCA INVENTORY. HLTH & SFTY REPORTING LIST:CAS #67-63-0: EFTIVE DATE: DEC 15, 1986; SUNSET DATE: DEC 15, 1996. CHEM TEST RULES: CAS #67-63-0:TESTING REQD BY:MFRS, IMPORTERS; PROCESSORS (40. SECTION 12B:CAS #67-63-0:EXPORT NOTIFICATION REQD - SECTION 4. TSCA SIGNIFICANT NEW USE RULE:NONE OF CHEMS IN THIS MATL HAVE SNUR UNDER TS CA. CLEAN AIR ACT:THIS MATL DOES NOT CNTN ANY HAZ AIR POLLUTANTS. THIS MATL DOES NOT CNTN ANY CLASS 1 OZONE DEPLETORS. THIS MATL DOES NOT CNTN ANY CLASS 2 OZONE DEPLETORS. CLEAN WATER ACT:NONE OF CHEMS IN THIS PROD ARE LISTED (OTHER INFO) State Regulatory Information:CAS #67-63-0 CAN BE FOUND ON FOLLOWING STATE RIGHT TO KNOW LISTS: CALIFORNIA, NEW JERSEY, FLORIDA, PENNSYLVANIA, MINNESOTA, MASSACHUSETTS. CAS #77-09-8 IS NOT PRESENT ON STATE LISTS FROM CA, PA, MN, M A, FL OR NJ. CALIFORNIA NO SIGNIFICANT RISK LEVEL:NONE OF CHEMS IN THIS PROD ARE LISTED. -- SARA TITLE III: ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV. ======================= Other Information ======================= Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. 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