FISHER SCIENTIFIC, CHEMICAL DIV. -- SODIUM SALICYLATE, S395500 -- 6810-00N027915
===================== Product Identification ===================== Product ID:SODIUM SALICYLATE, S395500 MSDS Date:02/21/1991 FSC:6810 NIIN:00N027915 === Responsible Party === Company Name:FISHER SCIENTIFIC, CHEMICAL DIV. Address:1 REAGENT LANE City:FAIR LAWN State:NJ ZIP:07410 Country:US Info Phone Num:201-796-7100 OR 201-796-7523 Emergency Phone Num:201-796-7100/800-424-9300(CHEMTREC) CAGE:1B464 === Contractor Identification === Company Name:FISHER SCIENTIFIC CO. CHEMICAL MFG DIV Address:1 REAGENT LANE Box:City:FAIRLAWN State:NJ ZIP:07410-2802 Country:US Phone:201-796-7100 CAGE:1B464 ============= Composition/Information on Ingredients ============= Ingred Name:ING 9: EFTS ON NEWBORN HAVE BEEN RPTD FROM A SINGLE EXPOS IN MICE. CHRONIC-RPTD/PRLNG CONT MAY CAUSE TINNITUS, (ING 11) RTECS #:9999999ZZ Ingred Name:ING 10: ABNORM BLEEDING, GASTRIC ULCERATION, WEIGHT LOSS, MENTAL DETERIORATION, & SKIN ERUPTION. VISUAL DISTURB (ING 12) RTECS #:9999999ZZ Ingred Name:ING 11: WERE RPTD AFTER INGEST OF 8-20 GRAMS IN COURSE OF SEVERAL DAYS. VISION FADED TO COMPLETE BLINDNESS W/IN (ING 13) RTECS #:9999999ZZ Ingred Name:ING 12: SEVERAL HRS. BLINDNESS LASTED 3-24 HRS. HOWEVER, NORMAL VISION GRADUALLY RETURNED. RARE OPTICAL EFTS MAY(ING 14) RTECS #:9999999ZZ Ingred Name:ING 13: INCL NARROWING OF VISUAL FIELDS, HEMIANOPSIA & NYSTAGMUS. LIVER DMG MAY ALSO OCCUR. EFTS ON NEWBORN HAVE(ING 15) RTECS #:9999999ZZ Ingred Name:ING 14: BEEN RPTD FROM REPEATED ADMIN TO RATS/MICE. EFTS ON EMBRYO/FETUS HAVE BEEN RPTD FROM REPEATED EXPOSURE TO RATS. RTECS #:9999999ZZ Ingred Name:FIRST AID PROC: SALINE, OCCAS LIFTING UPPER/LOWER LIDS, UNTIL NO EVIDENCE OF CHEM REMAINS (APPROX 15-20 MIN). (ING 17) RTECS #:9999999ZZ Ingred Name:ING 16: GET MED ATTN IMMED. INGEST: IF CONSCIOUS & NOT CONVL, INDUCE EMESIS BY GIVING SYRUP OF IPECAC FOLLOWED (ING 18) RTECS #:9999999ZZ Ingred Name:ING 17: BY WATER. IF VOMIT OCCURS KEEP HEAD BELOW HIPS TO PVNT ASPIR. REPEAT IN 20 MIN IF NOT EFTIVE INITIALLY. (ING 19) RTECS #:9999999ZZ Ingred Name:ING 18: GIVE ACTIVATED CHARCOAL. IN PATIENTS W/DEPRESS RESP OR IF EMESIS IS NOT PRDCED, PERFORM GASTRIC LAVAGE (ING 20) RTECS #:9999999ZZ Ingred Name:ING 19: CAUTIOUSLY. TREAT SYMPTOMATICALLY/ SUPPORTIVELY. GASTRIC LAVAGE SHLD BE PERFORMED BY QUALIFIED MEDICAL (ING 21) RTECS #:9999999ZZ Ingred Name:ING 20: PERSONNEL. GET MEDICAL ATTENTION IMMEDIATELY. NO SPECIFIC ANTIDOTE. RTECS #:9999999ZZ Ingred Name:OTHER PROT EQUIP: THE IMMEDIATE WORK AREA FOR EMERGENCY USE. RTECS #:9999999ZZ Ingred Name:ING 8: DEVEL ABNORM HAVE BEEN RPTD FROM A SINGLE EXPOS TO RATS/MICE. EFTS ON EMBRYO/FETUS, EFTS ON FERTILITY & (ING 10) RTECS #:9999999ZZ Ingred Name:SALICYLIC ACID, MONOSODIUM SALT; (SODIUM SALICYLATE) CAS:54-21-7 RTECS #:VO5075000 Fraction by Wt: 100% Ingred Name:SUPP DATA: ALTERATIONS IN ACID-BASE BALANCE. CONVL/COMA MAY OCCUR. DEHYDRATION MAY OCCUR AS RSLT OF HYPERPYREXIA,(ING 3) RTECS #:9999999ZZ Ingred Name:ING 2: SWEATING/VOMIT & LOSS OF WATER VAP FROM HYPERVENT. OLIGURIA MAY OCCUR FROM TUBULAR NECROSIS. HEMORRHAGIC (ING 4) RTECS #:9999999ZZ Ingred Name:ING 3: PHENOMENA ARE OCCAS SEEN & MAY CONSIST OF PETECHIAL HEMORRHAGES ESPECIALLY AROUND EYELIDS, FACE & NECK, (ING 5) RTECS #:9999999ZZ Ingred Name:ING 4: RARELY THROMBOCYTOPENIC PURPURA, & BLEEDING FROM STOMACH/DUODENUM. HYPOGLYCEMIA, PANCREATITIS & SEV TOXIC (ING 6) RTECS #:9999999ZZ Ingred Name:ING 5: ENCEPHALOPATHY MAY ALSO OCCUR. AS POISONING PROGRESSES, CNS STIMULATION IS USUALLY REPLACED BY INCREASING (ING 7) RTECS #:9999999ZZ Ingred Name:ING 6: DEPRESS, STUPOR & COMA. CARDIOVASCULAR COLLAPSE & RESP INSUFFICIENCY ENSUE & TERMINAL ASPHYXIAL CONVL, (ING 8) RTECS #:9999999ZZ Ingred Name:ING 7: UREMIA & PULM EDEMA SOMETIMES APPEAR. DEATH MAY RSLT FROM RESP FAILURE AFTER A PERIOD OF UNCONSCIOUSNESS. (ING 9) RTECS #:9999999ZZ ===================== Hazards Identification ===================== LD50 LC50 Mixture:LD50: (ORAL, RAT) 1200 MG/KG Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO Health Hazards Acute and Chronic:SODIUM SALICYLATE IS A POWERFUL IRRITANT/CNS DEPRESSANT. INHAL: ACUTE/CHRONIC-NO DATA AVAIL. SKIN: ACUTE-MAY CAUSE IRRIT/SENSIT W/RASHES & SKIN ERUPTIONS. IT IS ABSORBED THRU SKIN & MAY CAUSE SYMPTOMS AS IN ACUTE INGEST. CHRONIC-RPTD/PRLNGCONT MAY CAUSE SENSIT DERMAT & SYMPTOMS AS IN CHRONIC INGEST. (EFTS OF OVEREXP) Explanation of Carcinogenicity:NOT RELEVANT. Effects of Overexposure:HLTH HAZ: EYE: ACUTE/CHRONIC-NO DATA AVAIL. INGEST: ACUTE-MAY CAUSE BURNING PAIN IN MOUTH/GI IRRIT. EXPOS TO VERY EXCESSIVE AMTS OF SALICYLATES MAY CAUSE HDACH/DIZZ/RINGING IN EARS/DFCLTY IN HEARING/D IMNESS OF VISION/MENTAL CONFUSION/LASS/DROW/SWEATING/THIRST/NAUS/VOMIT/HYPERVENT/FLUID RETENTION & OCCAS (SUPP DATA) Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER. ======================= First Aid Measures ======================= First Aid:INHAL: REMOVE FROM EXPOS AREA TO FRESH AIR IMMED. IF BRTHG HAS STOPPED, PERFORM ARTF RESP. KEEP WARM/AT REST. TREAT SYMPTOMATICALLY/SUPPORTIVELY. GET MED ATTN IMMED. SKIN: REMOVE CONTAMD CLTHG/ SHOES IMMED. WASH AFFECTED AREA W/SOAP OR MILD DETERGENT & LG AMTS OF WATER UNTIL NO EVIDENCE OF CHEM REMAINS (APPROX 15-20 MIN). GET MED ATTN IMMED. EYES: WASH IMMED W/LG AMTS OF WATER OR NORMAL (ING 16) ===================== Fire Fighting Measures ===================== Extinguishing Media:DRY CHEMICAL, CARBON DIOXIDE, WATER SPRAY OR REGULAR FOAM. FOR LARGER FIRES, USE WATER SPRAY, FOG OR REGULAR FOAM. Fire Fighting Procedures:MOVE CONTR FROM FIRE AREA IF YOU CAN DO IT W/O RISK. DO NOT SCATTER SPILLED MATL W/HIGH-PRESS WATER STREAMS. DIKE FIRE-CTL WATER FOR LATER DISPOSAL. (SUPP DATA) Unusual Fire/Explosion Hazard:SLIGHT FIRE HAZARD WHEN EXPOSED TO HEAT OR FLAME. ================== Accidental Release Measures ================== Spill Release Procedures:SWEEP UP AND PLACE IN SUITABLE CLEAN, DRY CONTAINERS FOR RECLAMATION OR LATER DISPOSAL. DO NOT FLUSH SPILLED MATERIAL INTO SEWER. KEEP UNNECESSARY PEOPLE AWAY. Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER. ====================== Handling and Storage ====================== Handling and Storage Precautions:KEEP CONTAINER TIGHTLY CLOSED. PROTECT FROM EXPOSURE TO AIR OR LIGHT. OBSERVE ALL FEDERAL, STATE AND LOCAL REGULATIONS WHEN STORING THIS SUBSTANCE. Other Precautions:NONE SPECIFIED BY MANUFACTURER. ============= Exposure Controls/Personal Protection ============= Respiratory Protection:HIGH LEVELS - NIOSH/MSHA APPROVED DUST MASK. Ventilation:PROVIDE LOCAL EXHAUST OR GENERAL DILUTION VENTILATION SYSTEM. Protective Gloves:IMPERVIOUS GLOVES . Eye Protection:CHEM WORK GOGG/FULL LENGTH FSHLD . Other Protective Equipment:IMPERVIOUS CLTHG/EQUIP TO PVNT RPTD/PRLNG SKIN CONT W/SUBSTANCE. EYE WASH FOUNTAIN/QUICK DRENCH SHOWER WITHIN (ING 22) Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER. Supplemental Safety and Health FIRE FIGHT PROC: USE AGENTS SUITABLE FOR TYPE OF SURROUNDING FIRE. AVOID BRTHG HAZ VAPS. KEEP UPWIND. WEAR NIOSH/MSHA APPRVD PRESS DEMAND SCBA & FULL PROT EQUIP . EFTS OF OVEREXP: DIARR. A MORE SEV DEGREE OF SALICYLATE INTOX IS CHARACT BY MORE PRONOUNCED CNS DISTURB/CARDIAC ABNORM/SKIN ERUPTIONS & MARKED (ING 2) ================== Physical/Chemical Properties ================== HCC:C3 pH:5-6 Solubility in Water:111% Appearance and Odor:ODORLESS WHITE CRYSTALS OR AMORPHOUS POWDER WITH A SLIGHT SALINE TASTE. ================= Stability and Reactivity Data ================= Stability Indicator/Materials to Avoid:YES AVOID CONTACT WITH STRONG OXIDIZERS. Stability Condition to Avoid:STABLE UNDER NORMAL TEMP/PRESS. MAY BURN BUT DOES NOT IGNITE READILY. AVOID EXCESSIVE HEAT, SPARKS, OR OPEN FLAME. Hazardous Decomposition Products:THERMAL DECOMPOSITION PRODUCTS MAY INCLUDE TOXIC OXIDES OF CARBON. ==================== Disposal Considerations ==================== Waste Disposal Methods:OBSERVE ALL FEDERAL, STATE AND LOCAL REGULATIONS WHEN DISPOSING THIS SUBSTANCE. FOR ASSISTANCE, CONTACT THE DISTRICT DIRECTOR OF THE ENVIRONMENTAL PROTECTION AGENCY. 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