Material Safety Data Sheet
4-Dimethylaminopyridine, 99%
ACC# 01954
Section 1 - Chemical Product and Company Identification |
MSDS Name: 4-Dimethylaminopyridine, 99%
Catalog Numbers:
AC148270000, AC148270050, AC148270250, AC148271000, NC9078520,
XXAC14827-2.5K
Synonyms:
gamma-(Dimethylamino)pyridine; p-Dimethylaminopyridine; DMAP; 4-DMAP;
N,N-Dimethyl-4-pyridinamine.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
1122-58-3 |
4-Dimethylaminopyridine |
99 | 214-353-5 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: white crystals.
Danger! May be fatal if absorbed through the skin.
Causes eye and skin burns. Causes digestive and respiratory tract
burns. Harmful if swallowed. Harmful if inhaled. May cause central
nervous system effects.
Target Organs: Central nervous system, eyes,
skin, mucous membranes.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
May be fatal if absorbed through the skin. Causes skin burns.
Substance is readily absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause severe and permanent damage to the
digestive tract.
Inhalation:
Harmful if inhaled. May cause severe irritation of the respiratory
tract with possible burns.
Symptoms of overexposure may include headache, nausea,
disorientation, weakness, convulsions, and possibly, death.
Chronic:
No information found.
Section 4 - First Aid Measures
|
Eyes:
In case of contact, immediately flush eyes with plenty of water for a
t least 15 minutes. Get medical aid immediately.
Skin:
In case of contact, immediately flush skin with plenty of water for
at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give
anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: 110 deg C ( 230.00 deg F)
Autoignition Temperature: 420 deg C ( 788.00 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 3; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Minimize dust generation and
accumulation. Do not get in eyes, on skin, or on clothing. Keep
container tightly closed. Do not ingest or inhale. Discard
contaminated shoes. Use only with adequate ventilation.
Storage:
Keep container closed when not in use. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from
incompatible substances.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
4-Dimethylaminopyridine
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
4-Dimethylaminopyridine:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
|
Physical State: Crystals
Appearance: white
Odor: characteristic odor
pH: 9.7 (10% aq soln)
Vapor Pressure: Negligible.
Vapor Density: Not available.
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: 162 deg C @ 50 mm Hg
Freezing/Melting Point:110-113 deg C
Decomposition Temperature:Not available.
Solubility: Slightly soluble.
Specific Gravity/Density:Not available.
Molecular Formula:C7H10N2
Molecular Weight:122.17
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, cyanides.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 1122-58-3:
US9230000
LD50/LC50:
CAS# 1122-58-3:
Oral, rat: LD50 =
250 mg/kg;
Skin, rabbit: LD50 = 13
mg/kg;
.
Oral, rat: LD50 = 95-140 mg/kg (Bayer)
l, rabbit: LD50 = 95
mg/kg (Bayer)
Carcinogenicity:
CAS# 1122-58-3:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No data available.
Teratogenicity:
No data available.
Reproductive Effects:
No data available.
Mutagenicity:
No data available.
Neurotoxicity:
No data available.
Other Studies:
Section 12 - Ecological Information
|
No information available.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
TOXIC SOLIDS, CORROSIVE, ORGANIC, N.O.S. |
TOXIC SOLID ORGANIC NOS (4-DIMETHYLAMINOPYRIDINE) |
Hazard Class: |
6.1 |
6.1 |
UN Number: |
UN2928 |
UN2811 |
Packing Group: |
II |
II |
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 1122-58-3 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 1122-58-3: immediate.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 1122-58-3 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T C
Risk Phrases:
R 34 Causes burns.
R 24/25 Toxic in contact with skin and if swallowed.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 28A After contact with skin, wash immediately with plenty of water
.
WGK (Water Danger/Protection)
CAS# 1122-58-3: No information available.
Canada - DSL/NDSL
CAS# 1122-58-3 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of E, D1A.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
Section 16 - Additional Information
|
MSDS Creation Date: 6/02/1998
Revision #3 Date: 10/03/2005
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.