CALBIOCHEM -- DEOXYCHOLIC ACID, SODIUM SALT, 264101  -- 6505-00N092484
<pre>=====================  Product Identification  =====================

Product ID:DEOXYCHOLIC ACID, SODIUM SALT, 264101
MSDS Date:02/24/1999
FSC:6505
NIIN:00N092484
Status Code:A
=== Responsible Party ===
Company Name:CALBIOCHEM
Box:12087
City:LA JOLLA
State:CA
ZIP:92039-2087
Country:US
Info Phone Num:800-854-3417; 619-450-5558
Emergency Phone Num:(800)424-9300
Resp. Party Other MSDS Num.:264101
Chemtrec Ind/Phone:(800)424-9300
CAGE:29089
=== Contractor Identification ===
Company Name:CALBIOCHEM
Box:12087
City:LA JOLLA
State:CA
ZIP:92039-2087
Country:US
Phone:619-450-5558; 800-854-3417
CAGE:29089

=============  Composition/Information on Ingredients  =============

Ingred Name:DEOXYCHOLIC ACID SODIUM SALT  LD50: (ORAL, RAT) 1370 MG/KG
CAS:302-95-4
RTECS #:FZ2250000
= Wt:100.

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:SEE INGRED & TOXICOLOGICAL INFO
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:MAY BE HARMFUL BY INGESTION,
    INHALATION OR ABSORPTION THROUGH SKIN. MATERIAL MAY CAUSE
    IRRITATION TO THE EYES, SKIN, MUCOUS MEMBRANES AND THE UPPER
    RESPIRATORY TRACT.
Effects of Overexposure:SEE HEALTH HAZARDS.

=======================  First Aid Measures  =======================

First Aid:SKIN: IN CASES OF SKIN CONTACT, WASH IMMED W/COPIOUS AMOUNTS
    OF WATER FOR AT LEAST 15 MINUTES. REMOVE CONTAMINATED CLOTHING AND
    SHOES AND WASH BEFORE WEARING. CONSULT A MD. EYES: IN CASES OF EYE
    CONTA CT, FLUSH IMMED W/COPIOUS AMOUNTS OF WATER FOR AT LEAST 15
    MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING EYELIDS W/FINGERS.
    CONSULT A MD. INHAL: IN CASES OF INHALATION, REMOVE TO FRESH AIR
    AND MONIT OR BREATHING. IF BREATHING BECOMES DIFFICULT, GIVE OXYGEN
    AND CONSULT A MD. IF BREATHING STOPS, GIVE ARTIFICIAL RESPIRATION
    AND CONSULT A MD. INGEST: IN CASES OF INGESTION, WASH MOUTH OUT
    W/WATER AND  CONSULT LOCAL POISON CENTER AND A MD.

=====================  Fire Fighting Measures  =====================

Extinguishing Media:DRY CHEMICAL POWDER, CARBON DIOXIDE, WATER SPRAY,
    ALCOHOL OR POLYMER FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
    EQUIPMENT  TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:UPON THERMAL DECOMPOSITION, IT MAY EMIT
    TOXIC GASES.

==================  Accidental Release Measures  ==================

Spill Release Procedures:EVACUATE AREA. WEAR A NIOSH APPROVED
    RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER
    GLOVES. SWEEP UP AND PLACE IN A SUITABLE CONTAINER. AVOID RAISING
    DUST. HOLD FOR APPROPRIATE DIS POSAL. WASH SPILL SITE AND VENTILATE
    AREA AFTER MATERIAL PICKUP IS COMPLETE.

======================	Handling and Storage  ======================

Handling and Storage Precautions:STORE IN A TIGHTLY CLOSED CONTAINER IN
    A COOL, DRY PLACE (+20C). PROTECT FROM MOISTURE. MATERIAL IS
    HARMFUL AND AN IRRITANT. AVOID CONTACT W/MATERIAL. AVOID PROLONGED
    OR REPEATED EXPOSURE. LAB SHOULD  BE EQUIPPED WITH A SAFETY SHOWER
    AND AN EYE WASH STATION. WASH THOROUGHLY AFTER HANDLING MATERIAL.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:USE A NIOSH APPROVED RESPIRATOR.
Ventilation:HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves:CHEMICAL RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH AND DELUGE SHOWER .
    WEAR SUITABLE PROTECTIVE CLOTHING.
Supplemental Safety and Health
DEOXYCHOLIC ACID, SODIUM SALT - MOLECULAR WEIGHT: 414.6; MOLECULAR
    FORMULA: C*24H*39O*4-NA.

==================  Physical/Chemical Properties  ==================

Solubility in Water:SOLUBLE
Appearance and Odor:OFF-WHITE SOLID.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
N/A.
Stability Condition to Avoid:N/A. STABLE UNDER NORMAL HANDLING
    PROCEDURES.
Hazardous Decomposition Products:UPON THERMAL DECOMPOSITION, MAY EMIT
    TOXIC GASES INCLUDING CARBON MONOXIDE AND CARBON DIOXIDE.

===================  Toxicological Information	===================

Toxicological Information:RTECS NUMBER: FZ2250000. TOXICITY DATA &
    REFERENCES: ORAL; RAT LD50: 1370 MG/KG ALTERED SLEEP; ATAXIA 1969.
    OYO YAKURI. PHARMACOMETRICS. 3, 45. ORAL; MUS; LD50: 1050 MG/KG
    SOMNOLENCE; ULCERATION/BLEED ING FROM STOMACH & SMALL INTESTINE
    1985. EISEI SHIKENJO HOKOKU. BULLETIN OF THE INSTITUTE OF HYGIENIC
    SCIENCES. (103), 29. IPR; RAT; LD50: 123 MG/KG ALTERED SLEEP;
    ATAXIA 1969. OYO YAKURI. PHARMACOMET RICS. 3, 45. IPR; MUS; LD50:
    36 MG/KG EXCITATION; HYPERMOTILITY; DIARRHEA 1985. EISEI SHIKENJO
    HOKOKU. BULLETIN OF THE INSTITUE OF HYGIENIC SCIENCES. (103), 29.
    IVN; RAT; LD50: 150 MG/KG 1970. (ECOLOG ICAL INFO)

=====================  Ecological Information  =====================

Ecological:NO INFORMATION AVAILABLE. --TOXICOLOGICAL INFO:
    ARZNEIMITTEL-FORSCHUNG. DRUG RESEARCH. 20, 323. IVN; MUS; LD50: 107
    MG/KG 1952. ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE
    THERAPIE. 90, 18. SCU;  MUS; LD50: 815 MG/KG ALTER SLEEP; ATAXIA
    1969. OYO YAKURI. PHARMACOMETRICS. 3, 45. REPRODUCTIVE EFFECTS AND
    REFERENCES: IPR; RAT; DOSE: 1400 MG/KG TOXIC PATERNAL EFFECTS 1969.
    OYO YAKURI. PHARMACOMET RICS. 3, 45. GENETIC DATA & REFERENCES:
    FBR; HMN; DOSE: 25 MG/L UNSCHEDULED DNA SYNTHESIS 1991. NUTRITION
    AND CANCER. 16, 227. LYM; HMN; DOSE: 100 MG/L DNA INHIBITION 1982.
    BULLETIN OF (TRANSPORT INFO )

====================  Disposal Considerations  ====================

Waste Disposal Methods:COUNTY, FEDERAL, STATE AND LOCAL REGULATIONS ARE
    VARIED AND CHANGE FREQUENTLY. FOR THIS REASON, WE RECOMMEND THAT
    YOU CONTACT YOUR LOCAL DEPARTMENT OF HEALTH SERVICES FOR
    INFORMATION ON DISPOSAL OF TH IS PRODUCT OR ARRANGE FOR DISPOSAL BY
    A LICENSED DISPOSAL COMPANY.

===================  MSDS Transport Information  ===================

Transport Information:UN NUMBER: N/A. PROPER SHIPPING NAME: N/A. IATA
    CLASS: N/A. IATA PACKING GROUP: N/A. --ECOLOGICAL INFO:
    ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY. 28, 504. REFER TO THE
    REGISTRY OF TOXIC EFFECTS OF C HEMICAL SUBSTANCES (RTECS) FOR A
    DEFINITION OF ABBREVIATIONS USED IN THE ABOVE TEXT AND FOR
    ADDITIONAL INFORMATION. THIS REPORT CONTAINS ONLY SELECTED
    INFORMATION FROM THE RTECS.

=====================  Regulatory Information  =====================

Federal Regulatory Information:RISK PHRASES: R20/21/22: HARMFUL BY
    INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED. R36/37/38;
    IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. SAFETY PHRASES:
    S22: DO NOT BREATHE DUST. S24/25: AVO ID CONTACT WITH SKIN AND
    EYES. S26: IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH
    PLENTY OF WATER AND SEEK MEDICAL ADVICE. S36/37/39: WEAR SUITABLE
    PROTECTIVE CLOTHING, GLOVES AND EYE/FACE PROT ECTION. S45: IN CASE
    OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE IMMEDIATELY.
State Regulatory Information:

=======================  Other Information  =======================

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