ALDRICH CHEMICAL CO INC. -- THEOPHYLLINE  -- 6505-01-093-9475
<pre>=====================  Product Identification  =====================

Product ID:THEOPHYLLINE
MSDS Date:11/01/1993
FSC:6505
NIIN:01-093-9475
=== Responsible Party ===
Company Name:ALDRICH CHEMICAL CO INC.
Address:1001 W. ST. PAUL AVE
Box:355
City:MILWAUKEE
State:WI
ZIP:53201
Country:US
Info Phone Num:800-325-5832 800231-8237
Emergency Phone Num:800-325-5832 800231-8237
CAGE:60928
=== Contractor Identification ===
Company Name:ALDRICH CHEMICAL CO INC
Address:1001 WEST ST PAUL AVE
Box:355
City:MILWAUKEE
State:WI
ZIP:53233
Country:US
Phone:414-273-3850
CAGE:60928
Company Name:SCHERING CORP PHARMACEUTICAL DIVISION
Address:1011 MORRIS AVE
Box:3185
City:UNION
State:NJ
ZIP:07083-1985
Country:US
Phone:908-820-4867
CAGE:1F095

=============  Composition/Information on Ingredients  =============

Ingred Name:THEOPHYLLINE
CAS:58-55-9
RTECS #:XH3850000
Other REC Limits:NONE RECOMMENDED

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:LD50 ORAL RABBIT=350 NG/KG(RTECS93-3)
Routes of Entry: Inhalation:NO	Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:SKIN:ABSORBED THROUGH SKIN,MODERATELY
    TOXICMAY CAUSE IRRITATION..EYES:MAY CAUSE IRRITATION.INHAL:MAY BE
    IRRITATING THE THE UPPER RESPIRATORY TRACT AND MUCOUS
    MEMBRANES.INGEST:TARGETS THE FOLLOWING ORG
    ANS:NERVES,HEART,KIDNEY,SMOOTH MUSCLES.
Explanation of Carcinogenicity:CLASSED IARC GROUP 3.
Effects of Overexposure:OVEREXPOSURE MAY
    CAUSENAUSEA,VOMITING,HEADACHE,DIARRHEA,EPIGASTRIC
    PAIN,HEMATEMESIS,INSOMNIA,CLONIC AND TONIC
    CONVULSIONS,TACHYCARDIA,HYPOTENSION,CIRCULATORY FAILURE,VENTRICULAR
    ARRYTHMIA.
Medical Cond Aggravated by Exposure:TOXIC SYNERGISM WITH
    EPINEPHRINE(AND OTHER SYMPATHOMIMETIC BRONCHODILATORS).

=======================  First Aid Measures  =======================

First Aid:EYES:FLUSH WITH WATER FOR 15 MINUTES.SKIN:REMOVE CONTAMINATED
    CLOTHING;WASH WITH WATER.INHAL:REMOVE TO FRESH AIR.GIVE OXYGEN OR
    ARTIFICIAL RESPIRATION IF NEEDED.INGEST:IF CONSCIOUS WASH OUT MOUTH
    WITH  WATER.CALL PHYSICIAN.

=====================  Fire Fighting Measures  =====================

Flash Point:NONE
Extinguishing Media:WATER SPRAY,CARBON DIOXIDE,DRY CHEMICAL POWDER OR
    APPROPRIATE FOAM.
Fire Fighting Procedures:USE A SELF-CONTAINED BREATHING APPARATUS AND
    FULL PROTECTIVE EQUIPMENT.
Unusual Fire/Explosion Hazard:TOXIC FUMES ARE EMITTED UNDER FIRE
    CONDITIONS.

==================  Accidental Release Measures  ==================

Spill Release Procedures:MATERIEL IS TABLET FORM.PICK UP AND PLACE IN
    AN APPROPRIATE CONTAINER FOR DISPOSAL.
Neutralizing Agent:NONE

======================	Handling and Storage  ======================

Handling and Storage Precautions:STORE IN A COOL,DRY PLACE.DO NOT
    BREATHE DUST.WASH HANDS AFTER HANDLING.
Other Precautions:MATERIEL IS TOXIC.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:USE APPROPRIATE NIOSH/MSHA APPROVED CHEMICALLY
    RESISTANT RESPIRATOR.
Ventilation:POWDERED FORM SHOULD ONLY BE HANDLED IN A CHEMICAL FUME
    HOOD.
Protective Gloves:AS NEEDED
Eye Protection:SAFETY GOGGLES
Other Protective Equipment:SAFETY SHOWER AND EYE WASH STATION.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
NONE

==================  Physical/Chemical Properties  ==================

HCC:N1
Melt/Freeze Pt:M.P/F.P Text:274F,134C
Appearance and Odor:TABLET;WHITE

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS
Stability Condition to Avoid:HIGH HEAT.
Hazardous Decomposition Products:CARBON MONOXIDE,CARBON DIOXIDE AND
    OXIDES OF NITROGEN.

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISSOLVE IN A COMBUSTIBLE SOLVENT AND INCINERATE
    IN A CHEMICAL INCINERATOR WITH SCRUBBER AND AFTERBURNER.DISPOSE OF
    IN ACCORDANCE WITH FEDERAL,STATE AND LOCAL REGULATIONS.

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