Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
100-02-7	4-Nitrophenol	>98%	202-811-7

Section 3 - Hazards Identification

Appearance: yellow crystals.
Light sensitive.
Target Organs: Blood, central nervous system.


Potential Health Effects
Eye: May cause eye irritation. Causes redness and pain.
Skin: May cause skin irritation. Harmful if absorbed through the skin. Causes symptoms similar to those of inhalation. Causes redness and pain. Substance is readily absorbed through the skin.
Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, and death. May cause effects similar to those for inhalation exposure. Effects may be delayed 2 to 4 hours. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood.
Inhalation: Harmful if inhaled. May cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). May cause respiratory tract irritation. May cause asthmatic attacks due to allergic sensitization of the respiratory tract. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown blood. May cause nausea and possible vomiting.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Repeated exposure may cause allergic respiratory reaction (asthma).

Section 4 - First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors or dust may form explosive mixture with air.
Extinguishing Media: Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: 169 deg C ( 336.20 deg F)
Autoignition Temperature: 283 deg C ( 541.40 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 1; Instability: 2

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Do not flush into a sewer. Avoid generating dusty conditions.

Section 7 - Handling and Storage

Handling: Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
4-Nitrophenol	none listed	none listed	none listed

OSHA Vacated PELs: 4-Nitrophenol: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Not available.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Crystals
Appearance: brown - yellow
Odor: phenol-like
pH: 4.4(5g/l aq.sol.)
Vapor Pressure: Not available.
Vapor Density: 4.4
Evaporation Rate:Not available.
Viscosity: 2.56mPa.s@121 deg C
Boiling Point: 279 deg C @ 760mmHg (dec)
Freezing/Melting Point:> 112 deg C
Decomposition Temperature:279 deg C
Solubility: 1.6 g/100 ml in water (25°C)
Specific Gravity/Density:Not available.
Molecular Formula:C6H5NO3
Molecular Weight:139.11

Section 10 - Stability and Reactivity

Chemical Stability: Stable.
Conditions to Avoid: Incompatible materials, light, temperatures above 75°C (167°F), heat.
Incompatibilities with Other Materials: Strong oxidizing agents, strong bases, caustic alkalis, combustible materials.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, irritating and toxic gases, carbon dioxide, phenol.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information

RTECS#:      
CAS# 100-02-7: SM2275000
LD50/LC50:
CAS# 100-02-7:
     Dermal, guinea pig: LD50 = >1 gm/kg;
     Oral, mouse: LD50 = 282 mg/kg;
     Oral, rat: LD50 = 202 mg/kg;
     Skin, rat: LD50 = 1024 mg/kg;
.

Carcinogenicity:
CAS# 100-02-7: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Mutagenicity: No data available.
Neurotoxicity: No data available.
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: Bacteria: Phytobacterium phosphoreum: LC50 = 37 mg/L; 30 min.; Microtox testDaphnia: Daphnia: LC50 = 37 mg/L; 24H; .Daphnia: Daphnia: LC50 = 37 mg/L; 24H; . log POW = 1.87
Environmental: No information available.
Physical: No information available.
Other: Avoid entering into waters or underground water. Do not empty into drains. Readily biodegradable.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series:
CAS# 100-02-7: waste number U170.

Section 14 - Transport Information

	US DOT	Canada TDG
Shipping Name:	NITROPHENOLS	NITROPHENOLS
Hazard Class:	6.1	6.1
UN Number:	UN1663	UN1663
Packing Group:	III	III

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 100-02-7 is listed on the TSCA inventory.
Health & Safety Reporting List
     CAS# 100-02-7: Effective 4/13/89, Sunset 6/30/98
Chemical Test Rules
     CAS# 100-02-7: subchronic toxicity testing for Health Effects
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 100-02-7: 100 lb final RQ (Listed under Nitrophenol, mixed); 45.4 kg final RQ (Listed unde
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 100-02-7: immediate, delayed, reactive.
Section 313
     This material contains 4-Nitrophenol (CAS# 100-02-7, >98%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR
Clean Air Act:
     CAS# 100-02-7 is listed as a hazardous air pollutant (HAP).
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 100-02-7 is listed as a Hazardous Substance under the CWA.      CAS# 100-02-7 is listed as a Priority Pollutant under the Clean Water      Act.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 100-02-7 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN
Risk Phrases:
     R 20/21/22 Harmful by inhalation, in contact with skin and if
     swallowed.
     R 33 Danger of cumulative effects.

Safety Phrases:
     S 28A After contact with skin, wash immediately with plenty of water
     .

WGK (Water Danger/Protection)
     CAS# 100-02-7: 2
Canada - DSL/NDSL
     CAS# 100-02-7 is listed on Canada's DSL List.
Canada - WHMIS
     not available.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 100-02-7 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 5/14/1998
Revision #3 Date: 10/08/2004

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.