Material Safety Data Sheet
Hexadecyltrimethylammonium bromide
ACC# 10815
Section 1 - Chemical Product and Company Identification |
MSDS Name: Hexadecyltrimethylammonium bromide
Catalog Numbers:
AC227160000, AC227160100, AC227160250, AC227161000, AC227165000,
AC411401000, AC411405000, NC9669840, O3042-500
Synonyms:
Cetrimide; Cetrimonium bromide; Palmityltrimethylammonium bromide;
N,N,N-Trimethyl-1-hexadecanaminium bromide; Cetyltrimethylammonium
bromide.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
57-09-0 |
Hexadecyltrimethylammonium bromide |
>99 | 200-311-3 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: white solid.
Warning! Harmful if swallowed. May cause allergic
skin reaction. May cause severe eye and skin irritation with
possible burns. May cause severe respiratory and digestive tract
irritation with possible burns. May cause central nervous system
effects. May cause cardiac disturbances. May cause reproductive and
fetal effects.
Target Organs: Central nervous system,
cardiovascular system.
Potential Health Effects
Eye:
May cause severe eye irritation. May result in corneal injury.
Skin:
May cause skin sensitization, an allergic reaction, which becomes
evident upon re-exposure to this material. May be absorbed through
the skin. May cause severe irritation and possible burns.
Ingestion:
Harmful if swallowed. May cause severe gastrointestinal tract
irritation with nausea, vomiting and possible burns.
Inhalation:
Causes respiratory tract irritation. May cause burns to the
respiratory tract. May cause cardiac abnormalities. May cause
Central Nervous System Effects characterized by apathy, mental
confusion, blurred vision, and tremors.
Chronic:
Repeated exposure may cause sensitization dermatitis.
Section 4 - First Aid Measures
|
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Immediately flush skin with plenty of water for at least 15 minutes
while removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid immediately. Do NOT induce vomiting. If conscious and alert,
rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing
is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Dusts at sufficient concentrations can form
explosive mixtures with air.
Extinguishing Media:
Use water spray, dry chemical, or carbon dioxide.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 2; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Avoid generating dusty conditions. Carefully scoop
up and place into appropriate disposal container. Provide
ventilation.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Minimize dust
generation and accumulation. Do not get on skin or in eyes. Do not
ingest or inhale.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible
substances.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
Hexadecyltrimethylammonium bromide
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
Hexadecyltrimethylammonium bromide:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Nitrile or Neoprene gloves are recommended.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
|
Physical State: Solid
Appearance: white
Odor: none reported
pH: Not available.
Vapor Pressure: Negligible.
Vapor Density: Not available.
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:470 deg F
Decomposition Temperature:470 deg F
Solubility: 10% in water.
Specific Gravity/Density:Not available.
Molecular Formula:C19H42BrN
Molecular Weight:364.2047
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable. However, may decompose if heated.
Conditions to Avoid:
Incompatible materials, dust generation, temperatures above 150°C.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 57-09-0:
BQ7875000
LD50/LC50:
CAS# 57-09-0:
Draize test, rabbit,
eye: 450 mg Severe;
Oral, rat: LD50
= 410 mg/kg;
.
Carcinogenicity:
CAS# 57-09-0:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information available.
Teratogenicity:
Embryo or Fetus: Stunted fetus, ipr-mouse TDLo=35mg/kg.
Specific Developmental Abnormalities: Craniofacial and
Musculoskeletal, ipr-mouse TDLo=10500ug/kg.
Reproductive Effects:
Fertility: Post-implantation mortality, ipr-mouse
TDLo=35mg/kg.
Mutagenicity:
No information available.
Neurotoxicity:
No information available.
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
No data available.
No information available.
Environmental:
No information reported.
Physical:
No information available.
Other:
None.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. |
No information available. |
Hazard Class: |
8 |
|
UN Number: |
UN3261 |
|
Packing Group: |
III |
|
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 57-09-0 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 57-09-0: immediate.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 57-09-0 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 22 Harmful if swallowed.
R 37 Irritating to respiratory system.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 57-09-0: 3
Canada - DSL/NDSL
CAS# 57-09-0 is listed on Canada's DSL List.
Canada - WHMIS
not available.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
Section 16 - Additional Information
|
MSDS Creation Date: 12/12/1997
Revision #5 Date: 3/04/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.